Bongkrekic acid CAS: 11076-19-0
MF: C28H38O7•3NH3
MW: 537.69
An apoptosis inhibitor through prevention of PARP cleavage.
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Bongkrekic acid (CAS 11076-19-0)

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See product citations (8)
Alternativa namn: Bongkrek acid; Flavotoxin A
Ansökan Bongkrekic acid is an apoptosis inhibitor through prevention of PARP cleavage
CAS Nr: 11076-19-0
Renhet: ≥98%
Molekylvikt: 537.69
Molekylär formel: C28H38O7•3NH3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

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Bongkrekic acid is a mitochondrial permeability transition pore blocker that acts as an inhibitory ligand of the mitochondrial adenine nucleotide translocator. This compound has been shown to inhibit apoptosis by preventing PARP cleavage and DEVDase activity.


Konferenser

1. Yoon, H.S., et al. 2000. Biochem Bioph Res Comun. 276:151-156. PMID: 11006098
2. Zamora, M., et al. 2004. FEBS Letters. 563:155-160. PMID: 15063741

Physical State :
Solid
Solubility :
Soluble in NH4OH (2N ), DMSO (100 mg/ml), and water.
LAGRING :
Store at -20° C
Melting Point :
50-60° C
Refractive Index :
n20D 1.55 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Merck Index :
14: 1332
MDL Number :
MFCD02179190
SMILES :
CC(CC=CCCC=CC=CCC(C(=CC=C(C)C(=O)O)C)OC)C=CC(=CC(=O)O)CC(=O)O.N.N.N

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Certificate of Analysis

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Bongkrekic acid (CAS 11076-19-0)  Produkt Citat

See how others have used Bongkrekic acid (CAS 11076-19-0). Click on the entry to view the PubMed entry .

Citations 1 to 8 of 8 total

PMID: # 29415987  Zhou, C. et al. 2018. Cell Death Dis. 9: 161.

PMID: # 25889084  Sulaiman, MK. et al. 2015. Mol. Cancer. 14: 78.

PMID: # 32821888  Photochem. Photobiol. Sci.

PMID: # 32291414  Oncogene. 4257-4270.

PMID: # 22272225  PLoS One. e28694.

PMID: # 32423794  Biochem. Biophys. Res. Commun.

PMID: # 26388407  Chem Biol Interact. 51-60.

PMID: # 32143825  Biochem. Biophys. Res. Commun.

Citations 1 to 8 of 8 total
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