BMS 195614 CAS: 253310-42-8
MF: C29H24N2O3
MW: 448.51
A neutral RARα (retinoic acid receptor α) inhibitor.

BMS 195614 (CAS 253310-42-8)

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Alternativa namn: BMS614
Ansökan BMS 195614 is a neutral RARα (retinoic acid receptor α) inhibitor
Momsregistreringsnummer :: 253310-42-8
Purity: ≥97%
Molecular Weight: 448.51
Molecular Formula: C29H24N2O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

BMS 195614 is a selective neutral RARα inhibitor and exhibits no significant effect on NCoR binding. The compound potentially decreases agonist-induced coactivator recruitment and SMRT binding to RAR. RARs, or Retinoic Acid Receptors, are nuclear hormone receptors that form heterodimers with RXRs (Retinoid X Receptors).

Physical State :
Solid
Solubility :
Soluble in DMSO (25 mM).
LAGRING :
Store at -20° C
Melting Point :
300.64° C (Predicted)
Boiling Point :
607.26° C at 760 mmHg (Predicted)
Density :
1.29 g/cm3 (Predicted)
Refractive Index :
n20D 1.69 (Predicted)
Ki Data :
Neutral retinoic acid receptor α: Ki= 2.5 nM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
445091
MDL Number :
MFCD00952209
SMILES :
CC1(CC=C(C2=C1C=CC(=C2)C(=O)NC3=CC=C(C=C3)C(=O)O)C4=CC5=CC=CC=C5N=C4)C

Download SDS (MSDS)

Certificate of Analysis

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