BMS 195614 is a selective neutral RARα inhibitor and exhibits no significant effect on NCoR binding. The compound potentially decreases agonist-induced coactivator recruitment and SMRT binding to RAR. RARs, or Retinoic Acid Receptors, are nuclear hormone receptors that form heterodimers with RXRs (Retinoid X Receptors).
Soluble in DMSO (25 mM).
Store at -20° C
300.64° C (Predicted)
607.26° C at 760 mmHg (Predicted)
1.29 g/cm3 (Predicted)
n20D 1.69 (Predicted)
Neutral retinoic acid receptor α: Ki= 2.5 nM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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