Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
BAR adaptor proteins primarily function to integrate signal transduction pathways that regulate nuclear processes, as well as the F-Actin cytoskeleton and overall membrane dynamics. BIN3 (Bridging integrator 3) is a 253 amino acid cytoplasmic protein that contains a BAR domain and is found to be expressed in all tissues except for brain. The BAR domain functions to influence transcriptional repression, to sense or induce membrane curvature at endocytic sites and to bind to small GTPases. The gene encoding BIN3 is localized to a cancer suppressing region that is frequently found to be deleted in non-Hodgkin's lymphomas and several epithelial tumors. The yeast homolog of BIN3 has found to be involved in vesicle trafficking, cell polarity, cytokinesis and F-Actin organization. There are 2 isoforms of BIN3 that exist as a result of alternative slicing events.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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