Aripiprazole-d8 CAS: 1089115-06-9
MF: C23H19D8Cl2N3O2
MW: 456.43
A selective dopamine D2-receptor antagonist.

Aripiprazole-d8 (CAS 1089115-06-9)

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Alternativa namn: 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl-d8]butoxy]-3,4-dihydrocarbostyril; 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl-d8]butoxy]-3,4-dihydro-2(1H)-quinolinone
Ansökan Aripiprazole-d8 is a selective dopamine D2-receptor antagonist
CAS Nr: 1089115-06-9
Molekylvikt: 456.43
Molekylär formel: C23H19D8Cl2N3O2
Kompletterande information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Aripiprazole-d8 is a deuterated version of Aripiprazole, which is a selective D2DR (dopamine D2-receptor) antagonist with dopamine autoreceptor agonist activity. Users have reported separation of this compound and aripiprazole under reverse-phase H and normal-phase.


Konferenser

1. Oshiro, Y., et al., 1998. Novel antipsychotic agents with dopamine autoreceptor agonist properties: synthesis and pharmacology of 7-[4-(4-phenyl-1-piperazinyl)butoxy]-3,4-dihydro-2(1H)-quinolinone derivatives. Journal of medicinal chemistry. 41(5): 658-67. PMID: 9513593
2. Cañive, J M., et al., 1998. Spontaneous brain magnetic activity in schizophrenia patients treated with aripiprazole. Psychopharmacology bulletin. 34(1): 101-5. PMID: 9580382

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in chloroform, and dichloromethane.
LAGRING :
Store at -20° C
Melting Point :
123-126° C
Boiling Point :
646.18° C at 760 mmHg (Predicted)
Density :
1.29 g/cm3 (Predicted)
Refractive Index :
n20D 1.59 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
RTECS :
VC8275950
PubChem CID :
SMILES :
[2H]C1(C(N(C(C(N1CCCCOC2=CC3=C(CCC(=O)N3)C=C2)([2H])[2H])([2H])[2H])C4=C(C(=CC=C4)Cl)Cl)([2H])[2H])[2H]

Download SDS (MSDS)

Certificate of Analysis

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