Anti-α-Dystrobrevin Antibody (D-9) is a mouse monoclonal IgG1 κ α-Dystrobrevin antibody, cited in 2 publications, provided at 200 µg/ml
raised against amino acids 301-600 deletion 366-422 (deletion 366-422) mapping within an internal region of α-Dystrobrevin of human origin
Anti-alpha-Dystrobrevin Antibody (D-9) is recommended for detection of all isoforms of α-Dystrobrevin of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
Anti-alpha-Dystrobrevin Antibody (D-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of α-Dystrobrevin (D-9): sc-271630.
m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for α-Dystrobrevin Antibody (D-9) for WB and IHC(P) applications. These reagents are now offered in bundles with α-Dystrobrevin Antibody (D-9) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
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Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
α-Dystrobrevin Antibody (D-9) is a high quality monoclonal alpha-Dystrobrevin antibody (also designated α-Dystrobrevin antibody) suitable for the detection of the alpha-Dystrobrevin protein of mouse, rat and human origin. α-Dystrobrevin Antibody (D-9) is available as both the non-conjugated anti-alpha-Dystrobrevin antibody form, as well as multiple conjugated forms of anti-alpha-Dystrobrevin antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Dystrobrevins are protein components of the dystrophin complex, whose disruption leads to Duchenne muscular dystrophy and related diseases. α-dystrobrevin is a dystrophin-related and -associated protein that is involved in synapse maturation and is required for normal muscle function. α-Dystrobrevin is a component of the dystrophin glycoprotein complex. It is localized to the cytoplasmic side of the sarcolemma and is highly concentrated at the neuromuscular junctions in skeletal muscle. The insertion of 57 amino acids by alternative splicing accounts for the increase in molecular mass of α-Dystrobrevin 1 in skeletal and cardiac muscle compared with brain and lung. α-Dystrobrevin containing complexes are found in endothelial and smooth muscle cells, while β-Dystrobrevin containing complexes are present at the basal region of renal epithelial cells. Additionally, β-Dystrobrevin is found in neurons and is highly enriched in postsynaptic densities. Alternative splicing of α-Dystrobrevin produces γ-Dystrobrevin (isoform 5), δ-Dystrobrevin (isoform 7), ε-Dystrobrevin (isoform 6) and ζ-Dystrobrevin (isoform 8). Additional isoforms may also exist.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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