A 582941 CAS: 848591-90-2
MF: C17H20N4
A 582941 is a selective AChR α7 partial agonist.

A 582941 (CAS 848591-90-2)

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Ansökan A 582941 is a selective AChR α7 partial agonist
Momsregistreringsnummer :: 848591-90-2
Purity: >98%
Molecular Weight: 280.37
Molecular Formula: C17H20N4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

A 582941 is a selective AChR α7 partial agonist. It exhibits high affinity for both rat and human α7 receptors (Ki values are 10.8 and 16.7 nM, respectively). A 582941 displays ~15-fold selectivity for α7 over 5-HT3 receptors (Ki = 150 nM for 5-HT3).

Physical State :
Solid
Solubility :
Soluble in DMSO (100 mM), and 1eq. HCl (50 mM).
LAGRING :
Desiccate at room temperature
Boiling Point :
497.40° C at 760 mmHg (Predicted)
Density :
1.16 g/cm3 (Predicted)
Refractive Index :
n20D 1.60 (Predicted)
Ki Data :
α7 nAChR: Ki= 10.8 nM (rat); α7 nAChR: Ki= 16.7 nM (human); 5-HT3: Ki= 150 nM
pK Values :
pKb: 9.65 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
MDL Number :
MFCD20926358

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Certificate of Analysis

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A 582941 (CAS 848591-90-2)  Produkt Citat

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PMID: # 32220620  Pharmacol. Biochem. Behav. 172916.

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