Anti-4.1R Antibody (B-11) is a mouse monoclonal IgG2a κ 4.1R antibody, cited in 3 publications, provided at 200 µg/ml
specific for an epitope mapping between amino acids 650-665 within an internal region of 4.1R of human origin
Anti-4.1R Antibody (B-11) is recommended for detection of 4.1R of mouse, rat and human origin by WB, IP, IF and ELISA
Anti-4.1R Antibody (B-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of 4.1R (B-11): sc-166759.
m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for 4.1R Antibody (B-11) for WB applications. These reagents are now offered in bundles with 4.1R Antibody (B-11) (see ordering information below).
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Labware ships FedEx Ground free of charge to the contiguous US
4.1R Antibody (B-11) is a high quality monoclonal 4.1R antibody (also designated 4.1R antibody) suitable for the detection of the 4.1R protein of mouse, rat and human origin. 4.1R Antibody (B-11) is available as both the non-conjugated anti-4.1R antibody form, as well as multiple conjugated forms of anti-4.1R antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The 4.1 gene family encodes a group of multifunctional cytoskeletal proteins (4.1R, 4.1G, 4.1N and 4.1B), which are predominantly expressed in the nervous system. 4.1G is a protein that stabilizes spectrin-actin interactions and is associated with hereditary elliptocytosis. Red blood cell 4.1, designated 4.1R, is a multifunctional protein that is essential for maintaining erythrocyte shape and membrane mechanical properties. Both 4.1R and 4.1G are distributed in a unique pattern in the cerebellum and are believed to modulate the membrane mechanical properties of neuronal cells by promoting fodrin/actin association. 4.1N and 4.1B, designated EPB41L1 and EPB41L3, respectively, are strongly expressed in the brain. Antibodies to 4.1N have been reported to detect mulitple forms, each enriched in postsynaptic density preparations relative to brain homogenate. Antibodies to 4.1B have been reported to detect two forms.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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