Santa Cruz Biotechnology offers a variety of gene editing products to target synthesis and degradation proteins using the CRISPR/Cas9 system. Proteolytic degradation is essential for normal cell cycle progression, cellular differentiation and stress responses. Degradation proteins are necessary to catalyze the breakdown of the extracellular matrix during processes such as embryonic development, reproduction, tissue remodeling, arthritis and metastasis. Synthesis and degradation proteins also play a necessary role in the activation of apoptosis pathways. To knockdown expression of synthesis and degradation proteins, Santa Cruz Biotechnology offers target-specific CRISPR/Cas9 Knockout (KO) Plasmids and CRISPR Double Nickase Plasmids.To activate transcription of synthesis and degradation protein genes, Santa Cruz Biotechnology offers target-specific CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems.
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