ZnAF-2 DA A fluorescent reagent used to detect zinc

ZnAF-2 DA (CAS 357339-96-9)

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Synonym: 6-[N-[N',N'-bis(2-Pyridinylmethyl)-2-aminoethyl]amino-3',6'-bis(acetyloxy)-spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one
Application: A fluorescent reagent used to detect zinc
CAS Number: 357339-96-9
Molecular Weight: 656.68
Molecular Formula: C38H32N4O7
* Refer to Certificate of Analysis for lot specific data (including water content).
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ZnAF-2 DA is a cell permeable derivative of ZnAF-2. A fluorescent reagent employed in the detection of low concentrations of zinc ion due to its strong affinity for the zinc ion. Zinc can be found in every cell in the human body. The zinc ion can be specifically detected.


References

1. Maruyanma, S., et al. 2000. J. Am. Chem. Soc. 124: 10650-10651. PMID: 12207508
2. Ueno, S., et al. 2002 J. Cell Biol. 158: 215-220. PMID: 12119362
3. Hirano, T., et al. 2002 J. Am. Chem. Soc. 124: 6555-6562 .PMID: 12047174

Formulation :
~5mM in DMSO
Physical State :
Liquid
Solubility :
Soluble in DMSO.
Storage :
Store at -20° C
Refractive Index :
n20D 1.70 (Predicted)
Fluoresence :
λex 492 nm, λem 515 nm in PBS, Zn2+, esterase
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
16760714
MDL Number :
MFCD08702725
SMILES :
CC(=O)OC1=CC2=C(C=C1)C3(C4=C(O2)C=C(C=C4)OC(=O)C)C5=C(C=CC(=C5)NCCN(CC6=CC=CC=N6)CC7=CC=CC=N7)C(=O)O3

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Certificate of Analysis

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