Zinquin ethyl ester A lipophilic, zinc-sensitive, cell-permeable fluorescnet probe

Zinquin ethyl ester (CAS 151606-29-0)

Zinquin ethyl ester | CAS 151606-29-0 is rated 5.0 out of 5 by 1.
  • y_2019, m_6, d_19, h_2
  • bvseo_bulk, prod_bvrr, vn_bulk_2.0.12
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_222427, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 147ms
  • REVIEWS, PRODUCT
Synonym: (2-Methyl-8-(4-methylphenylsulfonylamino)quinolinyl)oxyacetic acid ethyl ester
Application: A lipophilic, zinc-sensitive, cell-permeable fluorescnet probe
CAS Number: 151606-29-0
Purity: ≥97%
Molecular Weight: 414.48
Molecular Formula: C21H22N2O5S
* Refer to Certificate of Analysis for lot specific data (including water content).
submit a review for this product and receive 15 cruzcredits

Zinquin ethyl ester is a lipophilic, zinc-sensitive, cell-permeable fluorescent probe. It can be found in living cells because the ethyl ester is cleaved by cytosolic esterase to give Zinquin that carry a negative charge, preventing its efflux across the plasma membrane.


References

Correlation of apoptosis with change in intracellular labile Zn(II) using zinquin [(2-methyl-8-p-toluenesulphonamido-6-quinolyloxy)acetic acid], a new specific fluorescent probe for Zn(II): P.D. Zalewski, et al.; Biochem. J. 296, 403 (1993) Flux of intracellular labile zinc during apoptosis (gene-directed cell death) revealed by a specific chemical probe, Zinquin: P.D. Zalewski, et al.; Chem. Biol. 1, 153 (1994) Measurement of zinc in hepatocytes by using a fluorescent probe, zinquin: relationship to metallothionein and intracellular zinc: P. Coyle, et al.; Biochem. J. 303, 781 (1994) Video image analysis of labile zinc in viable pancreatic islet cells using a specific fluorescent probe for zinc: P.D. Zalewski, et al.; J. Histochem. Cytochem. 42, 877 (1994) Intracellular zinc movement and its effect on the carbohydrate metabolism of isolated rat hepatocytes: I.A. Brand & J. Kleineke; J. Biol. Chem. 271, 1941 (1996)

Physical State :
Solid
Solubility :
Soluble in DMSO, methanol, 100% ethanol, water (slightly), and dichloromethane.
Storage :
Store at -20° C
Melting Point :
112-114° C
Boiling Point :
~578.0° C at 760 mmHg (Predicted)
Density :
~1.3 g/cm3 (Predicted)
Refractive Index :
n20D 1.62 (Predicted)
Fluoresence :
λex 360 nm, λem 480 nm in DMSO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
3638243
MDL Number :
MFCD00797629
SMILES :
CCOC(=O)COC1=CC(=C2C(=C1)C=CC(=N2)C)NS(=O)(=O)C3=CC=C(C=C3)C

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 56ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Rated 5 out of 5 by from Various publications cite Zinquin ethyl ester Various publications cite Zinquin ethyl ester as a lipophilic, zinc-sensitive, cell-permeable fluorescent probe. -SCBT Publication Review
Date published: 2015-02-23
  • y_2019, m_6, d_19, h_2
  • bvseo_bulk, prod_bvrr, vn_bulk_2.0.12
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_222427, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 3ms
  • REVIEWS, PRODUCT

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.