Click on image or enlarge button to enlarge

Z-WEHD-FMK

Synonym: Benzyloxycarbonyl-Trp-Glu(OMe)-His-Asp(OMe)-fluoromethylketone

Application: An inhibitor of caspase-1, caspase-4, caspase-5 and caspase-8

Molecular Weight: 763.78

Molecular Formula: C₃₇H₄₂FN₇O₁₀

* Refer to Certificate of Analysis for lot specific data (including water content).

Submit a review for this product and receive 15 CruzCredits

QUICK LINKS

SDS & Certificate of Analysis

Z-WEHD-FMK is a potent, cell-permeable, and irreversible inhibitor of caspase-5. It also inhibits caspase-1, caspase-4 and caspase-8. Caspase inhibitors play an important role in investigating biological processes. The caspase family of proteins function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Following use of the inhibitor, standard apoptosis assays can then be used to examine treated cells for evidence of apoptosis.
For the fluorometric determination of caspase-6 activity, the following caspase apoptosis detection kit is available from Santa Cruz: Caspase-6 Kit (sc-4266 AK).

Physical State :

Solid

Sequence :

Z-Trp-Glu(OMe)-His-Asp(OMe)-FMK

Storage :

Store at -20° C

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

PubChem CID :

25108687

SMILES :

COC(=O)CC[C@@H](C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CC(=O)OC)C(=O)CF)NC(=O)[C@H](CC2=CNC3=CC=CC=C32)NC(=O)OCC4=CC=CC=C4

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

--%>

The email address or password you have entered is incorrect. Hide

* Required fields

Email*

Password*

Forgot your password?

SIGN IN WITH SOCIAL ACCOUNT

Please sign in using your account on one of the following social networks.

{* mergeAccounts {"custom": true} *}

{| rendered_current_photo |}

{| current_displayName |}
{| current_emailAddress |}

{| foundExistingAccountText |}.

{| moreInfoHoverText |}

{| moreInfoText |}

{| rendered_existing_provider_photo |}

{| existing_displayName |}
{| existing_provider_emailAddress |}

Created {| existing_createdDate |} at {| existing_siteName |}

Connect with your {| existing_siteName |} account?

{* backButton *}

{| connect_button |}

Don't have an account?

Email address already exists, please enter a new valid email address. Hide

* Required fields

PERSONAL INFORMATION

First Name*

Last Name*

LOGIN INFORMATION

Email*

Password*

Confirm Password*

Why create an account?

Creating an account with us makes your shopping experience much easier and faster. You can save favorites, save cart, check order status and speed through checkout with saved addresses, payment methods and more.

Already have an account?

Choose a Store

Choose a Language

Choose a Currency