WAY 262611 A WNT pathway agonist

WAY 262611

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 127ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Synonym: DKK1 inhibitor; (1-(4-(Naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-yl)methanamine
Application: A WNT pathway agonist
Purity: ≥97%
Molecular Weight: 318.42
Molecular Formula: C20H22N4
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

WAY 262611 is a Wnt pathway agonist acting via inhibition of DKK1 with no GSK-3β inhibition (IC50 value >100 μM). TCF-Luciferase EC50 = 0.63 μM.

Physical State :
Solid
Solubility :
Soluble in DMSO (30 mg/ml), or 100% ethanol (25 mg/ml).
Storage :
Store at -20° C
IC50 :
TCF-Luciferase: EC5050 = 0.63 µM; Dkk-1: EC5050 = 0.63 µM (human); GSK-3β: IC50 > 100 µM (human)
pK Values :
pKb: 10.13 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
25199517
SMILES :
C1CN(CCC1CN)C2=NC=CC(=N2)C3=CC4=CC=CC=C4C=C3

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

WAY 262611  Product Citations

See how others have used WAY 262611. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 27864382  Sima, J. et al. 2016. Development.

Citations 1 to 1 of 1 total
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 92ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 82ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.