VU 0155041 sodium salt A potent, positive allosteric mGluR-4 modulator

VU 0155041 sodium salt

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 71ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Application: A potent, positive allosteric mGluR-4 modulator
Purity: >99%
Molecular Weight: 338.16
Molecular Formula: C14H14Cl2NNaO3
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

Ordering Information

PRODUCT NAME CATALOG # UNIT PRICE QTY FAVORITES
VU 0155041 sodium salt sc-204386 10 mg $59.00
VU 0155041 sodium salt sc-204386A 50 mg $189.00

VU 0155041 sodium salt is the sodium salt preparation of VU 0155041(sc-204385), a positive allosteric modulator of the mGluR-4 (metabotropic glutamate receptor 4). Allosteric modulation of the mGluR-4 by VU 0155041 has been demonstrated to decrease haloperidol-induced catalepsy and reserpine-induced akinesia in rats, and has been correlated to antiparkinsonian effects. VU 0155041 sodium salt is an activator of mGluR-4.


References

1. Niswender, C.M., et al. 2008. Mol. Pharmacol. 74: 1345-1358. PMID: 18664603
2. Williams, R., et al. 2009. Bioorg. Med. Chem. Lett. 19: 4967-4970. PMID: 19640716

Physical State :
Solid
Solubility :
Soluble in water (25 mM).
Storage :
Desiccate at room temperature
IC50 :
mGlu4 receptors: EC5050 = 693 nM (rat); mGluR-4: EC5050 = 798 nM (human)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
2933724
MDL Number :
MFCD11519971
SMILES :
[Na]OC(=O)[C@@H]1CCCC[C@@H]1C(=O)Nc1cc(Cl)cc(Cl)c1

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

You May Also Like

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 75ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 7ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2017 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.