Vildagliptin A CD26 inhibitor associated with immune response inhibition

Vildagliptin (CAS 274901-16-5)

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Synonym: LAF237
Application: A CD26 inhibitor associated with immune response inhibition
CAS Number: 274901-16-5
Purity: ≥97%
Molecular Weight: 303.40
Molecular Formula: C17H25N3O2
* Refer to Certificate of Analysis for lot specific data (including water content).
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Vildagliptin is a dipeptidyl peptidase-4 (CD26) inhibitor. CD26 activates serine proteases in immune/inflammatory cells. Vildagliptin also inhibits dipeptidyl-peptidase 8 (DPRP1) and dipeptidyl-peptidase 9 (DPRP2), which have been correlated to T cell activation and immune function, as well as diabetes and cancer regulation.


1. Ahrén, B. et al. 2004. J. Clin. Endocrinol. Metab. 89(5): 2078-2084. PMID: 15126524

2. Ahrén, B. et al. 2004. Diabetes Care. 27(12): 2874-2880. PMID: 15562200

3. Barlocco, D. 2004. Curr Opin Investig Drugs. 5(10): 1094-1100. PMID: 15535431

Physical State :
Solubility :
Soluble in DMSO and Water
Storage :
Store at -20° C
Melting Point :
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :

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Vildagliptin  Product Citations

See how others have used Vildagliptin. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 25297967  Kawaguchi, T. et al. 2014. Hepatol. Res.

Citations 1 to 1 of 1 total

What is the stability of the powder at -20°C ?

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