Ursodeoxycholic Acid, Sodium Salt A steroid which reduces hydrophobic bile acids

Ursodeoxycholic Acid, Sodium Salt (CAS 2898-95-5)

Ursodeoxycholic Acid, Sodium Salt | CAS 2898-95-5 is rated 5.0 out of 5 by 1.
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Synonym: Sodium Ursodeoxycholate; UDCA
Application: A steroid which reduces hydrophobic bile acids
CAS Number: 2898-95-5
Purity: ≥98%
Molecular Weight: 414.55
Molecular Formula: C24H39NaO4
* Refer to Certificate of Analysis for lot specific data (including water content).
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Ursodeoxycholic Acid, Sodium Salt reduces hydrophobic bile acids and decreases both lymphocyte reactivity and serum alkaline phosphatase levels. It has also been shown to interfere with ileal absorption of toxic endogenous bile acids.


References

1. Oh, A.R. et al. 2016. BMB Rep. 49(2): 105-110. PMID: 26350747

Physical State :
Solid
Solubility :
Soluble in water (200 mg/ml), ethanol (15 mg/ml), DMSO (10 mg/ml), and DMF (5 mg/ml).
Storage :
Store at room temperature
Refractive Index :
n20D 1.54 (Predicted)
Optical Activity :
α20/D 48.5°, c = 2 in water
IC50 :
M1-family aminopeptidase: IC50 = 2.6 µM (Plasmodium falciparum 3D7); NTCP: IC50 = 3.6 µM (human); HCT-116: IC50 = >50 µM (human); GBM: IC50 = >50 µM (human)
Ki Data :
Asbt: Ki= 75 µM (human)
pK Values :
pKa: 4.76 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
23707110
Merck Index :
14: 9889
MDL Number :
MFCD00065453
SMILES :
C[C@H](CCC(=O)[O-])[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C.[Na+]

Download SDS (MSDS)

Certificate of Analysis

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Ursodeoxycholic Acid, Sodium Salt  Product Citations

See how others have used Ursodeoxycholic Acid, Sodium Salt. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 26351365  Sousa, T. et al. 2015. Journal of lipid research. 56: 2158-71.

Citations 1 to 1 of 1 total
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Rated 5 out of 5 by from Oh Oh, AR. et al. (PubMed 26350747) reported that Ursodeoxycholic Acid, a steroid which reduces hydrophobic bile acids, decreased age-related adiposity and inflammation in mice. -SCBT Publication Review
Date published: 2015-04-21
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