Tween-20 A membrane protein solubilizing non-ionic surfactant

Tween-20 (CAS 9005-64-5)

Tween-20 | CAS 9005-64-5 is rated 5.0 out of 5 by 2.
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Synonym: Polysorbate 20
Application: A membrane protein solubilizing non-ionic surfactant
CAS Number: 9005-64-5
Molecular Weight: 1227.54
Molecular Formula: C58H114O26
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

Tween-20 is a non-ionic surfactant that is useful for solubilizing membrane proteins during isolation. Tween-20 is also added to buffers for immunohistochemistry. Tween-20 may also help to prevent non-specific antibody binding and function as a blocking agent in immunoblotting assays.


References

1. Batteiger, B., et al. 1982. J. Immunol. Methods. 55: 297-307. PMID: 6820029
2. Towbin, H. and Gordon, J. 1984. J. Immunol. Methods. 72: 313-340. PMID: 6206159
3. Spinola, S.M. and Cannon, J.G. 1985. J. Immunol. Methods. 81: 161-165. PMID: 3926901
4. Black, P.N., et al. 1987. J. Biol. Chem. 262: 1412-1419. PMID: 3027089
5. Albu, D.I., et al. 2010. Methods Mol. Biol. 647: 377-390. PMID: 20694680

Physical State :
Liquid
Solubility :
Soluble in water.
Storage :
Store at room temperature
Boiling Point :
>100° C
Density :
1.105 g/mL at 20° C
Refractive Index :
n20D 1.47
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
RTECS :
TR7400000
PubChem CID :
9892973
MDL Number :
MFCD00165986
EC Number :
500-018-3
SMILES :
CCCCCCCCC=CCCCCCCCC(=O)OCCOCC(C1C(CC(O1)OCCO)OCCO)OCCO

Download SDS (MSDS)

Certificate of Analysis

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Tween-20  Product Citations

See how others have used Tween-20. Click on the entry to view the PubMed entry .

Citations 1 to 10 of 19 total

PMID: # 26957540  Wang, Z. et al. 2016. J. Biol. Chem. 291: 10646-58.

PMID: # 26114658  Zhou, J. et al. 2015. Autophagy. 11: 1259-79.

PMID: # 24962405  Ahn, JH. et al. 2014. J. Vet. Sci. 15: 335-42.

PMID: # 19623194  Li, D. et al. 2009. J. Cereb. Blood Flow Metab. epub.

PMID: # 19060135  Harriff, MJ. et al. 2009. J. Bacteriol. 191: 1132-1142.

PMID: # 19393114  Siddiqui, RA. et al. 2009. Br. J. Nutr. 102: 967-975.

PMID: # 18427549  Frederick, LA. et al. 2008. Oncogene. 27: 4841-4853.

PMID: # 17912546  Wagner, N. et al. 2008. Pflugers Arch. 455: 839-487.

PMID: # 16712839  Yegorova, S. et al. 2006. Exp. Eye Res. 83: 783-792.

PMID: # 16230611  Stepulak, A. et al. 2005. Proc. Natl. Acad. Sci. U.S.A. 102: 15605-15610.

Citations 1 to 10 of 19 total

Is sc-29113 a 100% Tween-20 nonionic detergent or is this 10% T20 solution? Thank you!

Asked by: BeaRoma
Yes, this is 100% Tween-20 and not a diluted solution.
Answered by: Technical Support
Date published: 2019-01-06

Is sc-29113, Tween-20 reagent grade or molecular grade?

Asked by: Jz28sail
Thank you for your question. The compound, sc-29113, is a high-quality reagent not marketed as a specific grade, nor do we purchase a specific grade. If you have any further questions or concerns, please feel free to contact our Technical Service department by calling 800-457-3801 option 2, emailing scbt@scbt.com, or using the Live Chat function on our website.
Answered by: Tech Service 8
Date published: 2017-01-26
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Rated 5 out of 5 by from Use it routinely in WB Use it routinely in WB, works good, no complaints
Date published: 2015-04-10
Rated 5 out of 5 by from Siddiqui Siddiqui, et. al. (PubMed ID 19393114) used product sc-29113 in wash and incubation buffers in WB analysis. -SCBT Publication Review
Date published: 2015-04-10
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