Taurolithocholic Acid Sodium Salt is a major human metabolite. It is a bile acid which inhibits radioligand binding to mAChR M1 (muscarinic M1), but not to M2 or M3 receptors.
Javitt, N.B., et al.: J. Clin. Invest., 47, 1002 (1968), Bowmer, C., et al.: J. Pharm. Pharmacol., 37, 812 (1985), Ha, C., et al.: J. Biomed. Sci., 7, 114 (2000), Zaton, A., et al.: Chem. Biol. Interact., 124, 1 (2000),
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For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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AmonyingcharoenAmonyingcharoen, S. et al. (PubMed 25815516) reported that Taurolithocholic Acid promotes intrahepatic cholangiocarcinoma cell growth via muscarinic acetylcholine receptor and EGFR/ERK1/2 signaling pathway. -SCBT Publication Review
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