Taurolidine is a broad spectrum antibiotic that was derived from the aminosulfoacid Taurine (sc-202354). Shown to be effective against aerobic, anaerobic, gram-negative and gram-positive bacteria as well as fungi and mycobacterium. Found to exhibit antitumor activity with low toxicity, antiangiogenic effects, antiendotoxin activity, and to induce apoptosis of tumor cells; thereby decreasing proliferation of the tumor cells (both in vitro and in vivo). Has been used in studies of alternative chemotherapeutics, and is shown to work synergistically with rhTRAIL (sc-4547) doubling the effects of Taurolidine alone. The synergistic response of Taurolidine and TRAIL may outline a new therapeutic strategy in oncology therapy.
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Soluble in DMSO (>20 mg/ml), and water.
Store at -20° C
189.55° C (Predicted)
471.21° C at 760 mmHg (Predicted)
1.47 g/cm3 (Predicted)
n20D 1.56 (Predicted)
pKa: 11.16 (Predicted), pKb: 2.54 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Certificate of Analysis
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See how others have used Taurolidine. Click on the entry to view the PubMed entry
What analytical method was used to obtain [Purity : ≥98%] ?
and, Is the water content checked?
Asked by: Kwon
Thank you for your question. This is lot-specific information. Each lot of this chemical comes with a lot-specific Certificate Of Analysis which typically describes the percent purity as well as the method used to determine the purity. You may request a lot-specific Certificate Of Analysis on our website. Alternatively, please contact our Technical Service Department to inquire about the purity of our most recent lot. Please call our Asian Support office toll-free at 800-820-8626, email firstname.lastname@example.org, or contact us by live chat.
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