Taurodeoxychloic acid An apoptosis inhibitor

Taurodeoxychloic acid (CAS 516-50-7)

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Synonym: Taurodeoxycholate
Application: An apoptosis inhibitor
CAS Number: 516-50-7
Molecular Weight: 499.70
Molecular Formula: C26H45NO6S
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Taurodeoxychloic Acid activates EGFR-dependent PI3K/Akt signaling in order to stop apoptosis in human colon cancer cells.


References

Cheng, K., et al.: Biochem. J., 330, 353 (1998), Cheng, K., et al.: Cancer Res., 63, 6744 (2003), Bellacosa, A., et al.: Adv. Cancer Res., 94, 29 (2005), Cheng, K., et al.: Biochem. Pharmacol., 70, 1035 (2005), Fang, D., et al.: J. Biol. Chem., 282, 11221 (2007),

Physical State :
Solid
Storage :
Store at -20° C
Density :
~1.4 g/cm3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
2733768
SMILES :
C[C@H](CCC(=O)NCCS(O)(=O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C

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Certificate of Analysis

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