TAPS, Sodium Salt A zwitterionic buffer with a useful pH range of 7.7 - 9.1

TAPS, Sodium Salt  (CAS 91000-53-2)

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Synonym: N-[Tris(hydroxymethyl)methyl]-3-aminopropanesulfonic acid sodium salt; [(2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]-1-propanesulfonic acid sodium-potassium salt; 3-[N-TRIS-(HYDROXYMETHYL)METHYLAMINO]PROPANESULPHONIC ACID, SODIUM SALT
Application: A zwitterionic buffer with a useful pH range of 7.7 - 9.1
CAS Number: 91000-53-2
Purity: ≥98%
Molecular Weight: 265.26
Molecular Formula: C7H16NO6SNa
* Refer to Certificate of Analysis for lot specific data (including water content).
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TAPS, Sodium Salt is a zwitterionic buffer used in biochemistry and molecular biology. It has a useful pH range of 7.7 - 9.1. TAPS has been utilized in capillary electrophoresis of such materials as DNA and DNA-dye complexes. Dyes have been separated by planar chromatography with electroosmotic flow with 1 mM TAPS in the mobile phase. The stability constants of metal ions with TAPS have been investigated by capillary electrophoresis. TAPS has also been shown to inhibit connexin channel activity. The activity of various mutants of carbonic anhydrase I and carbonic anhydrase II has been studied in a variety of buffers, including TAPS.


References

1. Good, N.E., et al. 1966. Biochemistry. 5: 467-477. PMID: 5942950

Appearance :
Crystalline
Physical State :
Solid
Solubility :
Soluble in water (333.33 mg/ml).
pH :
useful range 7.7 - 9.1
Storage :
Store at room temperature
Refractive Index :
n20D ~1.56 (Predicted)
pK Values :
pKa: 8.4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
16219995
MDL Number :
MFCD00069903
SMILES :
C(CNC(CO)(CO)CO)CS(=O)(=O)O.[Na]

Download SDS (MSDS)

Certificate of Analysis

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