Sultriecin is a dominant analogue in a family of triene antibiotics isolated as a sodium salt from Streptomyces. Despite the structural similarity to fostriecin, there is little comparative data to support a common mode of action. Sultriecin is reported t.o display potent antifungal and antitumor activity.
1. Ohkuma, H., et al., 1992. Sultriecin, a new antifungal and antitumor antibiotic from Streptomyces roseiscleroticus. Production, isolation, structure and biological activity. The Journal of antibiotics. 45(8): 1239-49. PMID: 1399844
2. Burke, Christopher P., et al., 2010. Total synthesis, assignment of the relative and absolute stereochemistry, and structural reassignment of phostriecin (aka Sultriecin). Journal of the American Chemical Society. 132(7): 2157-9. PMID: 20108904
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