Sultriecin A dominant analog in a family of triene antibiotics

Sultriecin (CAS 131774-59-9)

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Synonym: BU 3285T
Application: A dominant analog in a family of triene antibiotics
CAS Number: 131774-59-9
Purity: >98%
Molecular Weight: 492.47
Molecular Formula: C23H34NaO8P
* Refer to Certificate of Analysis for lot specific data (including water content).
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Sultriecin is a dominant analogue in a family of triene antibiotics isolated as a sodium salt from Streptomyces. Despite the structural similarity to fostriecin, there is little comparative data to support a common mode of action. Sultriecin is reported t.o display potent antifungal and antitumor activity.


References

1. Ohkuma, H., et al., 1992. Sultriecin, a new antifungal and antitumor antibiotic from Streptomyces roseiscleroticus. Production, isolation, structure and biological activity. The Journal of antibiotics. 45(8): 1239-49. PMID: 1399844
2. Burke, Christopher P., et al., 2010. Total synthesis, assignment of the relative and absolute stereochemistry, and structural reassignment of phostriecin (aka Sultriecin). Journal of the American Chemical Society. 132(7): 2157-9. PMID: 20108904

Appearance :
Powder
Physical State :
Solid
Derived From :
Streptomyces
Solubility :
Soluble in ethanol, methanol, DMF, DMSO or water.
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
23666703
SMILES :
CCCCC/C=C/C=C/C=C/C(C(C)C(C/C=C/C1C(C=CC(=O)O1)O)OS(=O)(=O)[O-])O.[Na+]

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Certificate of Analysis

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