Sulfamethazine A sulfonamide antibacterial

Sulfamethazine (CAS 57-68-1)

Sulfamethazine | CAS 57-68-1 is rated 5.0 out of 5 by 1.
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Synonym: Sulfadimidine; Sulfadimerazine
Application: A sulfonamide antibacterial
CAS Number: 57-68-1
Purity: ≥98%
Molecular Weight: 278.33
Molecular Formula: C12H14N4O2S
* Refer to Certificate of Analysis for lot specific data (including water content).
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Sulfamethazine is an antibacterial. Sulfamethazine blocks the synthesis of dihydrofolic acid by inhibiting dihydropteroate synthase. In addition, sulfamethazine is a structural analog and competitive antagonist of para-aminobenzoic acid (PABA) and can inhibit normal bacterial utilization of PABA for the synthesis of folic acid, which is an important metabolite in DNA synthesis.


References

Papostephanou, M., et al.: Anal. Profiles Drug Subs., 7, 401 (1978)

Physical State :
Solid
Solubility :
Soluble in DMSO (56 mg/mL at 25° C), water (<1 mg/mL at 25° C), and ethanol (<1 mg/mL at 25° C).
Storage :
Store at -20° C
Melting Point :
198-201° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
5327
SMILES :
CC1=CC(=NC(=N1)NS(=O)(=O)C2=CC=C(C=C2)N)C

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Li Li, X. et al. (PubMed 19680904) developed two immunoassay methods for the detection of the antibacterial Sulfamethazine in swine urine. -SCBT Publication Review
Date published: 2015-05-26
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