Sucrose monolaurate A non-ionic detergent used to solubilize membrane bound proteins"

Sucrose monolaurate (CAS 25339-99-5)

Sucrose monolaurate | CAS 25339-99-5 is rated 5.0 out of 5 by 1.
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Synonym: n-Monododecanoate-a-D-glucopyranoside; Sucrose monolaurate
Application: A non-ionic detergent used to solubilize membrane bound proteins"
CAS Number: 25339-99-5
Molecular Weight: 524.60
Molecular Formula: C24H44O12
* Refer to Certificate of Analysis for lot specific data (including water content).
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Sucrose monolaurate is a non-ionic detergent for the solubilization of membrane proteins as has been observed in the removal of β-adrenergic receptors from turkey erythrocyte membranes and muscarinic acetylcholine receptors from porcine atria. The compound has demonstrated that at a concentration of 100 μg/ml to retard the replication of Listeria monocytogenesand has been lethal at 400μg/ml during the logarithmic growth phase.


References

1. Hooper, G. 1977. Respir Physiol. 31: 291-294. PMID: 609847
2. Fong, S.L., et al. 1982. Meth. Enzymol. 81: 133-140. PMID: 6980357
3. Rinken, A. and Haga, T. 1993. Arch. Biochem. Biophys. 301: 158-164. PMID: 8442658
4. Monk, J.D., et al. 1996. J. Appl. Bacteriol. 81: 7-18. PMID: 8675484

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in water (miscible).
Storage :
Store at 4° C
Melting Point :
150° C
Boiling Point :
721.62° C at 760 mmHg (Predicted)
Density :
1.37 g/cm3 (Predicted)
Refractive Index :
n20D 1.58 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
1
PubChem CID :
5360776
MDL Number :
MFCD00077947
EC Number :
246-873-3
Beilstein Registry :
65819
SMILES :
CCCCCCCCCCCC(=O)O[C@@]1([C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)[C@@]2([C@H]([C@@H]([C@H](O2)CO)O)O)CO

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Certificate of Analysis

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Rated 5 out of 5 by from Monk et al Monk et al. (PubMed ID 8675484) found that sucrose monolaurate was lethal to Listeria monocytes.
Date published: 2015-05-07
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