Sodium perchlorate, anhydrousA chaotropic agent used in DNA extraction and hybridization

Sodium perchlorate, anhydrous (CAS 7601-89-0)

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Synonym: Natriumperchloraat
Application: A chaotropic agent used in DNA extraction and hybridization
CAS Number: 7601-89-0
Purity: ≥98%
Molecular Weight: 122.44
Molecular Formula: NaClO4
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* Refer to Certificate of Analysis for lot specific data (including water content).
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Sodium perchlorate, anhydrous is a chaotropic agent used in standard DNA extraction and hybridization reactions in molecular biology. Often preferred over phenol extraction's because the sodium perchlorate/chloroform extraction technique is less time consuming and poses fewer hazards to the technician. Sodium perchlorate prevents binding of phenolic compounds to RNA during extraction. Eluent component used for analysis of biological samples by liquid chromatography. This compound is anhydrous.


References

1. Newbury, H.J., et al. 1977. Plant Physiol. 60: 543-547. PMID: 16660134
2. Johns, M.B., et al. 1989. Anal. Biochem. 180: 276-278. PMID: 2554754
3. Ma, H.W., et al. 1994. J Forensic Sci Soc. 34: 231-235. PMID: 7844515
4. Campanero, M.A., et al. 2004. J Chromatogr A. 103: 219-228. PMID: 15058586

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in water (2090 g/l at 15° C), and water (2840 g/l at 50° C).
Storage :
Store at room temperature
Melting Point :
482° C (lit.)
Density :
2.5 g/cm3 at 20° C
Ki Data :
Astrosclerin-3: Ki= 5.11 mM; Carbonic anhydrase I: Ki= >200 mM (human); Carbonic anhydrase II: Ki= >200 mM (human)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
1
RTECS :
SC9800000
PubChem CID :
522606
Merck Index :
14: 8653
MDL Number :
MFCD00003480
EC Number :
231-511-9
SMILES :
[O-]Cl(=O)(=O)=O.[Na+]

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Certificate of Analysis

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