Sodium iodideA useful reactant in the Finkelstein reaction

Sodium iodide (CAS 7681-82-5)

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Application: A useful reactant in the Finkelstein reaction
CAS Number: 7681-82-5
Purity: ≥99%
Molecular Weight: 149.89
Molecular Formula: NaI
* Refer to Certificate of Analysis for lot specific data (including water content).
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Sodium Iodide is a crystalline salt commonly used in the Finkelstein reaction via an SN2 pathway, detection of radiation, and in the conversion of an alkyl chloride into an alkyl iodide. When activated with thallium, Sodium Iodide can be subjected to ionizing radiation, emitting photons, which makes it essential in detecting gamma rays using scintillation detectors. Biologically, Sodium Iodide is used in PCR, the Sodium Iodide symporter, and to produce chemokines, particularly CCL2, CXCL8, and CXC14 by stimulation of thyroid follicular cells.


References

1. Tominaga, S. 1983. Radioisotopes. 32: 101-108. PMID: 6688137
2. Owono, A.P. 2010. J Environ Radioact. 101: 692-699. PMID: 20471729
3. Yamazaki, K. ,et al. 2010. Thyroid. 20: 67-76. PMID: 20025541

Appearance :
Crystalline
Physical State :
Solid
Solubility :
Soluble in water (1840 mg/ml at 25° C), alcohol, glycerol, and acetone. Insoluble in ether.
Storage :
Store at room temperature
Melting Point :
661° C (lit.)
Boiling Point :
1300-1304° C at 760 mmHg
Density :
3.67 g/cm3 at 20° C
Refractive Index :
n20D 1.77
Ki Data :
CA I: Ki= 0.3 mM (human); Astrosclerin-3: Ki= 10.4 mM (Astrosclera willeyana); CA II: Ki= 26 mM (human)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
1
RTECS :
WB6475000
PubChem CID :
5238
Merck Index :
14: 8631
MDL Number :
MFCD00003532
EC Number :
231-679-3
Beilstein Registry :
8127930
SMILES :
[Na+].[I-]

Download SDS (MSDS)

Certificate of Analysis

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What is the appearance of the compound?

Asked by: two2igm05
Thank you for your question. Sodium iodide, sc-203388, is in colorless crystal or powder form.
Answered by: Chemical Support 4
Date published: 2017-06-29
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