Sodium bicarbonate A commonly used laboratory pH neutralizer that reacts with acids and bases

Sodium bicarbonate (CAS 144-55-8)

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Synonym: Sodium hydrogen carbonate
Application: A commonly used laboratory pH neutralizer that reacts with acids and bases
CAS Number: 144-55-8
Purity: ≥99%
Molecular Weight: 84.01
Molecular Formula: NaHCO3
* Refer to Certificate of Analysis for lot specific data (including water content).
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Sodium bicarbonate is a commonly used laboratory chemical. The compound can react with both acids and bases, therefore it can be used as a neutralizer. When reacting with bases the compound forms carbonates. Sodium bicarbonate may be used to remove or wash acidic impurities from a crude liquid to yield a purer sample. Sodium bicarbonate reacts with the carboxyl groups to give a fast-forming and effervescent CO2 formation which has been used to test for the presence of carboxylic groups in proteins. Sodium bicarbonate has been observed to significantly decrease serum potassium levels as well as increase blood pH and bicarbonate concentration. The compound has been recorded to decrease the duration of peripheral nerve block in rats when when added to Lidocaine (sc-204056).


References

1. Chew, D.J., et al. 1991. Am. J. Vet. Res. 52: 12-17. PMID: 1850584
2. Sinnott, C.J., et al. 2000. Anesthesiology. 93: 1045-1052. PMID: 11020760
3. Holleman, A.F. and Wiberg, E. 2001. Inorganic Chemistry. San Diego, CA. Academic Press.

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in water (50 mg/ml). Insoluble in ethanol.
Storage :
Store at room temperature
Melting Point :
300° C
Density :
2.16 g/cm3 at 20° C
Refractive Index :
n20D 1.50
Ki Data :
CA IV: Ki= 6.6 mM (human); CA I: Ki= 12 mM (human); CA IX: Ki= 13 mM (human); Astrosclerin-3: Ki= 22.8 mM (human); CA II: Ki= 85 mM (human)
pK Values :
pKa: 6.37, 10.25 in carbonic acid(25°C)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
1
RTECS :
VZ0950000
PubChem CID :
516892
Merck Index :
14,8583
MDL Number :
MFCD00003528
EC Number :
205-633-8
Beilstein Registry :
4153970
SMILES :
C(=O)(O)[O-].[Na+]

Download SDS (MSDS)

Certificate of Analysis

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