sertaconazole nitrate CAS: 99592-39-9, MF: C20H15Cl3N2OS.HNO3, MW: 500.78, Purity: ≥98%

sertaconazole nitrate (CAS 99592-39-9)

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Application: CAS: 99592-39-9, MF: C20H15Cl3N2OS.HNO3, MW: 500.78, Purity: ≥98%
CAS Number: 99592-39-9
Purity: ≥98%
Molecular Weight: 500.78
Molecular Formula: C20H15Cl3N2OS.HNO3
* Refer to Certificate of Analysis for lot specific data (including water content).

Sertaconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme necessary to convert lanosterol to ergosterol. As ergosterol is an essential component of the fungal cell membrane, inhibition of its synthesis results in increased cellular permeability causing leakage of cellular contents. Sertaconazole may also inhibit endogenous respiration, interact with membrane phospholipids, inhibit the transformation of yeasts to mycelial forms, inhibit purine uptake, and impair triglyceride and/or phospholipid biosynthesis.

Appearance :
Crystalline powder
Physical State :
Solid
Solubility :
Soluble in DMSO (20 mg/ml), and methanol.
Storage :
Store at room temperature
Melting Point :
163-165° C
Refractive Index :
n20D ~1.68 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
200103
MDL Number :
MFCD00918063
SMILES :
C1=CC2=C(C(=C1)Cl)SC=C2COC(CN3C=CN=C3)C4=C(C=C(C=C4)Cl)Cl.[N+](=O)(O)[O-]

Download SDS (MSDS)

Certificate of Analysis

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What is the appearance of the compound?

Asked by: two2igm05
Thank you for your question. Sertaconazole nitrate, sc-280082, is in white or almost white powder form.
Answered by: Chemical Support 4
Date published: 2017-05-12
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