SB-415286 is an ATP-competitive inhibitor of GSK3α (Glycogen Synthase Kinase 3α) with a Ki value of 31 nM. SB-415286 displays similar potency for GSK-3β. Alternate studies suggest that SB-415286 stabilizes β-catenin, which in turn leads to inhibition of coxsackievirus-induced cell death.
1: A. Carabaza et al. Chirality 1997 9 281
Soluble in DMSO (72 mg/ml at 25° C), ethanol (72 mg/ml at 25° C), and water (< 1 mg/ml at 25° C).
bvseo-msg: The resource to the URL or file is currently unavailable.;
Rated 5 out of
Jiang et alJiang et al. (PubMed ID 24969790) found that SB-415286 showed a protective effect against radiation-induced necrosis via GSK-3 inhibition. -SCBT Publication Review
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn
Create a new account
Email address already exists, please enter a new valid email address.
USE YOUR SOCIAL NETWORK
Create an account quickly and easily with your preferred social network account. You won't have to remember an extra name and password.
Creating an account with us makes your shopping experience much easier and faster. You can save favorites, save cart, check order status and speed through checkout with saved addresses, payment methods and more.