[Sar-9, Met(O2)-11]-Substance P A selective NK1 receptor agonist

[Sar-9, Met(O2)-11]-Substance P (CAS 110880-55-2)

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Application: A selective NK1 receptor agonist
CAS Number: 110880-55-2
Purity: >97%
Molecular Weight: 1393.7
Molecular Formula: C64H100N18O15S
* Refer to Certificate of Analysis for lot specific data (including water content).
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Sar-9, Met(O2)-11]-Substance P is a highly selective NK-1R (NK-1 neurokinin receptor) agonist which stimulates endocytosis of NK-1 receptors but has minimal effect on NK-3 receptors. Studies suggest that this peptide does not insert into neutral or negatively charged lipid bilayers and densely packed lipid monolayers at surface pressures greater than 31 mN/m. Furthermore, in vitro tests show that Sar-9, Met(O2)-11]-Substance P augments the release of vasopressin from the hypothalamo-neurohypophysial system.


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Physical State :
Solubility :
Soluble in water (1 mg/ml), and 5% acetic acid.
Storage :
Store at -20° C
Density :
~1.44 g/cm3 (Predicted)
Refractive Index :
n20D 1.66
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
PubChem CID :
MDL Number :

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Certificate of Analysis

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