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ChiangChiang, KH. et al. (PubMed 26309120) analyzed the effects of Rosuvastatin Calcium Salt, a selective, competitive inhibitor of HMG-CoA reductase, treatments in recovery of capillary density and blood flow, the expression of vWF and CXCR4 at ischemia sites in hindlimb ischemia ICR mice. The results indicated that Rosuvastatin treatment led to significantly more CXCR4-positive endothelial progenitor cells incorporated into ischemic sites and in the blood compared with control mice. -SCBT Publication Review
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