Ro 01-6128An allosteric mGluR-1 activator

Ro 01-6128 (CAS 302841-86-7)

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Synonym: (Diphenylacetyl)-carbamic acid ethyl ester
Application: An allosteric mGluR-1 activator
CAS Number: 302841-86-7
Purity: ≥98%
Molecular Weight: 283.32
Molecular Formula: C17H17NO3
* Refer to Certificate of Analysis for lot specific data (including water content).
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Ro 01-6128 is a positive allosteric modulator of mGluR-1 and potentiates glutamate-induced calcium release (EC = 104.2 nM in rat mGluR-1a). Metabotropic glutamate group I receptors are coupled to Gq/11 and are activators of phospholipase C.

Physical State :
Solid
Solubility :
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage :
Store at 4° C
Melting Point :
196.61° C (Predicted)
Boiling Point :
465.78° C (Predicted)
Density :
1.16 g/cm3 (Predicted)
Refractive Index :
n20D 1.56 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
9903898
MDL Number :
MFCD20270619
SMILES :
CCOC(=O)NC(=O)C(C1=CC=CC=C1)C2=CC=CC=C2

Download SDS (MSDS)

Certificate of Analysis

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