RHOD 2/AM is a membrane permeable form of RHOD 2 which operates in the visible spectrum. Used as a fluorescent probe for intracellular Ca2+. RHOD 2/AM binds to Ca2+ once it is hydrolyzed to RHOD 2 by endogenous esterases inside cells.
1. Minta, A., et al. 1989. J. Biol. Chem. 264: 8171-8178. PMID: 2498308 2. Quinton, T.M., et al. 1992. Biochem. Biophys. Res. Commun. 184: 893-899. PMID: 1315537 3. Okada, M., et al. 1992. Brain Res. 583: 227-236. PMID: 1387038 4. Tamura, Y., et al. 1992. Brain Res. 592: 317-325. PMID: 1360313 5. Melamed, N., et al. 1993. J. Neurosci. 13: 632-649. PMID: 8426230
Soluble in DMSO, DMF, methanol, and chloroform.
Store at -20° C
λex 550 nm, λem 578 nm in methanol; λex 546 nm in CHCl3/CH3OH; λex 552 nm in Buffer pH 7 ; λex 549 nm, λem 578 nm in DMSO; λex 550 nm, λem 570 nm in Chloroform:Methanol (90:10)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Rated 5 out of
Duan ZZ; et alDuan ZZ; et al. (PubMed ID:26320687) utilized RHOD 2/AM to detect mitochondrial membrane potential and mitochondrial permeability transition pore (mPTP) opening. -SCBT Publication Review
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