Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
The small Ras-related protein Ran, also designated TC4, is a nuclear localized GTPase implicated in a diverse array of cellular processes including DNA replication, entry into and exit from mitosis, and the transport of RNA and proteins through the nuclear pore complex. Like Ras, active Ran GTP and inactive Ran GDP levels are tightly regulated by guanine nucleotide exchange factors (GEFs) and GTPase activating proteins (GAPs). Ran BP-M, also designated Ran-binding protein 9, is involved the nucleation of microtubule networks and may also act as an adapter protein in the coupling of membrane receptors to intracellular signaling pathways. It has been implicated in the activation of androgen and glucocorticoid receptor. Ran BP-M contains phosphorylated Serine residues. It can localize to both the nucleus and the cytoplasm, and a phosphorylated form can be associated with the plasma membrane. Ran BP-M is ubiquitously expressed, with highest expression levels in heart, testis, muscle and placenta. The enzymatic activity of the Ran BP-M protein is associated with breast cancer progression and fragile-X mental retardation.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.