R5C3 is an MDM2 inhibitor, 2-phenoxybenzoyl-tryptophan derivative. It is reported as a novel probe for high throughput fluorescence polarization binding assay and is useful in screening for small molecule inhibitors of MDM2-binding to p53.
Zhang, R., et al., Fluroescence polarization assay and inhibitor design for MDM2/p53 interaction. Anal. Biochem. 331, 138-146, (2004)
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