Quinacrine dihydrochloride is a non-specific PLA2 (phospholipase A2) inhibitor. Quinacrine, Dihydrochloride acts as an AChR (acetylcholine receptor) antagonist. Quinacrine dihydrochloride suppresses glibenclamide-sensitive K+-currents (IC50 = 4.4 μM). This compound also inhibits MAO (monoamine oxidase). Quinacrine, Dihydrochloride is an inhibitor of cPLA2, MAO-A and MAO-B.
Holscher, C. 1995. Neurobiol. Learn. Mem. 63, 206. Sakuta, H. and Yoneda, I. 1994. Eur. J. Pharmacol. 252, 117. Sargent, C.A., et al 1992. J. Pharmacol. Exp. Ther. 262, 1161. Voorhis, B.J., et al. 1992. Invertebr. Reprod. Dev. 21, 33. Murakami, M., et al. 1991. Biochem. Biophys. Res. Commun. 181,714.
Soluble in water (50 mg/ml with heat, yielding a clear solution), and ethanol (slightly). Insoluble in alcohol, benzene, chloroform, and ether.
Adobe Acrobat Reader is required to reliably view, print and comment on PDF documents
bvseo_sdk, java_sdk, bvseo-3.2.0
CLOUD, getContent, 66ms
bvseo-msg: The resource to the URL or file is currently unavailable.;
Rated 5 out of
Worked for our bacterial experiment!We purchased this project a few week ago and used it for our bacterial experiments. The quality was good.
Date published: 2018-08-02
Rated 5 out of
ZapataZapata-Mart nez, J. et al. (PubMed 26350822) investigated the involvement of phosphoinositide metabolism, especially the participation of PLA2 in dehydroleucodine (DhL)-induced activation of Rhinella arenarum oocytes. They found that introduction of Quinacrine, a non-specific PLA2 inhibitor, did not affect DhL-induced activation. -SCBT Publication Review
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn
Create a new account
Email address already exists, please enter a new valid email address.
USE YOUR SOCIAL NETWORK
Create an account quickly and easily with your preferred social network account. You won't have to remember an extra name and password.
Creating an account with us makes your shopping experience much easier and faster. You can save favorites, save cart, check order status and speed through checkout with saved addresses, payment methods and more.