QUIN 2, Tetrapotassium Salt A useful fluorescing calcium indicator

QUIN 2, Tetrapotassium Salt (CAS 73630-23-6)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 5ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Application: A useful fluorescing calcium indicator
CAS Number: 73630-23-6
Molecular Weight: 693.9
Molecular Formula: C26H23N3O10 4K
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

QUIN 2, Tetrapotassium Salt has been demonstrated to be an indicator of Zn2+-protein complexes.The binding of Ca2+ to QUIN 2 leads to a major shift in UV absorption spectrum and a twenty-fold enhancement in fluorescence quantum yield. TPEN (sc-200131) can be used in conjunction with QUIN 2 to reduce heavy-metal quenching of QUIN 2 fluorescence in cells. Spectral properties in the presence of low calcium concentrations (ex. 354 nm, em. 510 nm) differ from those during high calcium conditions (ex. 332 nm, em. 505 nm).


References

1. Komada, H., et al. 1989. Cell Struct. Funct. 14: 141. PMID: 2743418
2. Vijayaraghavan, S., et al. 1989. Cell Calcium 10: 241-253. PMID: 2776189
3. Arslan, P., et al. 1985. J. Biol. Chem. 260: 2719-2727. PMID: 3919006
4. Bryant, D.T. 1985. Biochem. J. 226: 613-616. PMID: 3994676
5. Grynkiewicz, G., et al. 1985. J. Biol. Chem. 260: 3440-3450. PMID: 3838314
6. Ashley R.H., et al. 1984. Biochem. J. 219: 149-158. PMID: 6326754
Tsien, R.Y., et al. 1982. J. Cell Biol. 94: 325-334. PMID: 6980885
Tsien, R.Y., et al. 1980. Biochemistry. 19: 2396-2404. PMID: 6770893

Physical State :
Solid
Solubility :
Soluble in water (10 mg/ml).
Storage :
Store at -20° C
Melting Point :
163.9-166.1° C
Boiling Point :
831.6° C at 760 mmHg (Predicted)
Fluoresence :
λex 332 nm, λem 493 nm in 0.1 M Tris pH 8.0, 10 mM Ca2+; λex 332-354 nm, λem 505-510 nm
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
135539
Merck Index :
14: 8042
MDL Number :
MFCD00065487
Beilstein Registry :
5374262
SMILES :
CC1=CC(=C(C=C1)N(CC(=O)[O-])CC(=O)[O-])OCC2=NC3=C(C=C(C=C3C=C2)OC)N(CC(=O)[O-])CC(=O)[O-].[K+].[K+].[K+].[K+]

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

To whom it may concern, My name is Akio Kikuchi from Dojindo Molecular Technologies, Inc. I would like to request a quote of 3000 mg of QUIN 2, Tetrapotassium Salt (CAS 73630-23-6). Could you please also tell me the current stock of QUIN 2?

Asked by: Akio
Thank you very much for your message. Our Customer Service Department will contact you by email.
Answered by: Technical Support Europe
Date published: 2018-01-11
  • y_2019, m_3, d_25, h_1CST
  • bvseo_bulk, prod_bvqa, vn_bulk_2.0.11
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_1
  • loc_en_US, sid_202303, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 32ms
  • QUESTIONS, PRODUCT
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 71ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.