Psammaplin A is an antibiotic, anti-tumor, DNA methyltransferase (Dnmt) inhibitor. It is a bromotyrosine-derived, symmetrical conjugate of cystamine, which was first isolated from the Psammaplinaplysilla sponge. Impedes angiogenesis as well as bacterial and tumor cell growth. Inhibits the activities of several key enzymes in prokaryotic and eukaryotic systems including those involved in epigenetic control of gene expression, DNA replication, angiogensis, and microbial detoxification.
1. Kim, T.H. et al. 2015. Biochim. Biophys. Acta. 1850(2): 401-410. PMID: 25445714
See how others have used Psammaplin A. Click on the entry to view the PubMed entry .
PMID: # 25749170 Mallol, A. et al. 2015. PLoS ONE. 10: e0120033.
PMID: # 25445714 Kim, TH. et al. 2015. Biochimica et biophysica acta. 1850: 401-10.
PMID: # 25068567 Mallol, A. et al. 2014. Cell Reprogram. 16: 392-406.
Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.