(+/-)-AC 7954 hydrochlorideA potent agonist of the GPR14 (urotensin II receptor)

(±)-AC 7954 hydrochloride (CAS 477313-09-0)

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Application: A potent agonist of the GPR14 (urotensin II receptor)
CAS Number: 477313-09-0
Molecular Weight: 366.28
Molecular Formula: C19H20ClNO2•HCl
* Refer to Certificate of Analysis for lot specific data (including water content).
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(±)-AC 7954 hydrochloride is a highly selective, non-peptide GPR14 (urotensin receptor) agonist that displays potent activity at human and rat UT receptors (pEC50 values are 6.5 and 6.7 respectively).


References

1. Croston, G.E., et al. 2002. J. Med. Chem. 45: 4950-4953. PMID: 12408704
2. Lavecchia, A., et al. 2005. J. Med. Chem. 48: 2480-2492. PMID: 15801838
3. Lehmann, F., et al. 2006. J. Med. Chem. 49: 2232-3340. PMID: 16570919

Physical State :
Solid
Solubility :
Soluble to 75 mM in Water and to 75 mM in DMSO
Storage :
Store at 4° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
9907171
SMILES :
CN(C)CCC1(CC2=CC=CC=C2C(=O)O1)C3=CC=C(C=C3)Cl.Cl

Download SDS (MSDS)

Certificate of Analysis

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