PIPES, Sesquisodium Salt PIPES Sesquisodium Salt, is a commonly utilized buffering agent

PIPES, Sesquisodium Salt (CAS 100037-69-2)

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Synonym: 1,4-Piperazinediethanesulfonic acid sesquisodium salt; Piperazine-1,4-bis(2-ethanesulfonic acid) sesquisodium salt; piperazine-N,N′-bis(2-ethanesulfonic acid)
Application: PIPES Sesquisodium Salt, is a commonly utilized buffering agent
CAS Number: 100037-69-2
Molecular Weight: 335.34
Molecular Formula: C8H16.5N2O6S21.5Na
* Refer to Certificate of Analysis for lot specific data (including water content).
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PIPES [piperazine-N,N′-bis(2-ethanesulfonic acid)] is frequently used as a buffering agent in biochemistry. It is an ethanesulfonic acid buffer developed by Good et al. in the 1960s. PIPES has a pKa near the physiological pH which makes it useful in cell culture work. It has been documented to minimize lipid loss when buffering glutaraldehyde histology in plant and animal tissues.


Additional forms available: PIPES, Free Acid (sc-216099); PIPES, Sesquisodium Salt (sc-216100); PIPES dipotassium salt (sc-258019); PIPES disodium salt (sc-264078); PIPES, Sodium Salt (sc-296097)


References

1. Good, N.E., et al. 1966. Biochemistry. 5: 467-477. PMID: 5942950
2. Schiff, R.I., et al. 1979. Scan Electron Microsc. 449-458. PMID: 118516
3. Yamamoto, K., et al. 1983. Histochemistry. 77: 339-351. PMID: 6305886
4. Blanchard, J.S. 1984. Meth. Enzymol. 104: 404-414. PMID: 6717292

Appearance :
Crystalline powder
Physical State :
Solid
Solubility :
Soluble in aqueous buffers or Water.
Storage :
Store at room temperature
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
3086462
MDL Number :
MFCD00066393
SMILES :
C1CN(CCN1CCS(=O)(=O)O)CCS(=O)(=O)[O-].C1CN(CCN1CCS(=O)(=O)[O-])CCS(=O)(=O)[O-].[Na+].[Na+].[Na+]

Download SDS (MSDS)

Certificate of Analysis

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