Phloxine B is a fluorescein dye which is known to inhibit the enzyme UDP-glucuronosyltransferase (UGT), the main catalyst for the glucuronidation of 7-HC. Additionally, Phloxine B is reported to be a poly(ADP-ribose) glycohydrolase (PARG) inhibitor. As a photoactive dye, Phloxine B is reported to have efficacy against gram-positive organisms. Phloxine B has also been utilized in a study investigating the visible light-induced photodegradation kinetics when coated onto silica TLC plates and in solution. The rapid photodegradation of Phloxine B via visible light exposure was noted and the phototoxicity of the remaining residues were also reported to be decreased.
1. Slabbert, J.C., et al. 1990. J Esthet Dent. 2: 177-180. PMID: 2088435
2. Wang, H., et al. 2008. Biomed. Environ. Sci. 21: 438-441. PMID: 19133619
3. Brovko, L.Y., et al. 2009. J. Food Prot. 72: 1020-1024. PMID: 19517729
4. van Midwoud, P.M., et al. 2010. Anal. Chem. [Epub ahead of print]. PMID: 21128611
See how others have used Phloxine B. Click on the entry to view the PubMed entry .
PMID: # 22291963
Tanae, K. et al. 2012. Histone chaperone Asf1 plays an essential role in maintaining genomic stability in fission yeast. PLoS ONE. 7: -.
Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2016 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.