Penicillin G potassium salt is a salt of Penicillin G. Penicillin G is a hydrophobic, β-lactam antibiotic produced by Penicillium spp. As an antibiotic, Penicillin G is noted to posses effectiveness mainly against gram-positive organisms. Some gram-negative organisms such as Neiserria gonorrhoeae and Neiserria meningitidis are also reported to be susceptible to Penicillin G. Penicillin G is also known as benzylpenicillin and contains a 6′ phenylacetyl side chain. In acid aqueous solutions, Penicillin is reported to decompose into penillic acid and penilloic acid. Penicillin G is also available as a non-salt (sc-344973) and in salt forms such as Penicillin G sodium (sc-257971).
1. Schwartz, M.A. 1965. J Pharm Sci. 54: 472-473. PMID: 14301592 2. Demain, A.L. 1991. Proc. Natl. Sci. Counc. Repub. China B. 15: 251-265. PMID: 1815263 3. Livermore, D.M. 2009. Curr. Protein Pept. Sci. 10: 397-400. PMID: 19538149
Soluble in water (100 mg/ml), methanol, ethanol (sparingly), and alcohol. Insoluble in chloroform.
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