PEG 1000 A polymer used to precipitate proteins, viruses, DNA and RNA

PEG 1000 (CAS 25322-68-3)

PEG 1000 | CAS 25322-68-3 is rated 5.0 out of 5 by 2.
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Synonym: Polyethylene Glycol 1000
Application: A polymer used to precipitate proteins, viruses, DNA and RNA
CAS Number: 25322-68-3
Molecular Weight: ~1000
Molecular Formula: HO(CH2-CH2-O)n-H
* Refer to Certificate of Analysis for lot specific data (including water content).
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PEG 1000 is a polyethylene Glycol is a polymer with a high affinity for water. When used at the proper concentration it can remove proteins from water. Generally the larger the protein the less PEG needed. Higher PEG polymers, PEG 4000-6000, have been used for DNA precipitation and even higher polymers, PEG 8000, can be used to precipitate DNA. PEG has also been used to recover pathogenic viruses and human rotaviruses from water, oyster and sediment samples. PEG has demonstrated to have anticell proliferation and antitumor effects via induction of apoptosis.


References

1. Lewis, G.D., et al. 1988. Appl. Environ. Microbiol. 54: 1983-1988. PMID: 2845860
2. Xu, Y., et al. 2004. Acta Crystallogr. D Biol. Crystallogr. 60: 2013-2015. PMID: 15502312
3. Fukuta, K., et al. 2008. Cancer Sci. 99: 1055-1062. PMID: 18380794

Appearance :
Chunks or flakes
Physical State :
Solid
Solubility :
H2O
pH :
5-7
Storage :
Store at room temperature
Melting Point :
37-40° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
1
RTECS :
TQ4025000
PubChem CID :
174
Merck Index :
14: 7568
MDL Number :
MFCD01779605
EC Number :
5000382
SMILES :
C(CO)O

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PEG 1000  Product Citations

See how others have used PEG 1000. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 18696092  Wegiel, J. et al. 2008. Acta Neuropathol. 116: 391-407.

Citations 1 to 1 of 1 total
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Rated 5 out of 5 by from I used this chemical for IHC in mouse tissues I used this chemical for IHC in mouse tissues and works well.
Date published: 2015-10-19
Rated 5 out of 5 by from Wegiel Wegiel, J. et al. (PubMed 18696092) embedded pretreated brain tissue in PEG 1000 and stored it at 4 C. These tissue blocks were then cut into serial sections, stored at room temperature in 70% ethyl alcohol, and used for immunocytochemical and morphometric studies. -SCBT Publication Review
Date published: 2015-04-10
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