PEG 1000 is a polyethylene Glycol is a polymer with a high affinity for water. When used at the proper concentration it can remove proteins from water. Generally the larger the protein the less PEG needed. Higher PEG polymers, PEG 4000-6000, have been used for DNA precipitation and even higher polymers, PEG 8000, can be used to precipitate DNA. PEG has also been used to recover pathogenic viruses and human rotaviruses from water, oyster and sediment samples. PEG has demonstrated to have anticell proliferation and antitumor effects via induction of apoptosis.
1. Lewis, G.D., et al. 1988. Appl. Environ. Microbiol. 54: 1983-1988. PMID: 2845860 2. Xu, Y., et al. 2004. Acta Crystallogr. D Biol. Crystallogr. 60: 2013-2015. PMID: 15502312 3. Fukuta, K., et al. 2008. Cancer Sci. 99: 1055-1062. PMID: 18380794
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For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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See how others have used PEG 1000. Click on the entry to view the PubMed entry
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Rated 5 out of
I used this chemical for IHC in mouse tissuesI used this chemical for IHC in mouse tissues and works well.
Date published: 2015-10-19
Rated 5 out of
WegielWegiel, J. et al. (PubMed 18696092) embedded pretreated brain tissue in PEG 1000 and stored it at 4 C. These tissue blocks were then cut into serial sections, stored at room temperature in 70% ethyl alcohol, and used for immunocytochemical and morphometric studies. -SCBT Publication Review
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