PD 153035 Hydrochloride is an extremely potent inhibitor of EGFR (epidermal growth factor receptor) tyrosine kinase (IC50 = 25 pM). Only inhibits other purified tyrosine kinases at micromolar or higher concentrations.
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Soluble in DMSO (10 mM) with gentle warming, water ( <1 mg/mL at 25° C), and ethanol ( <1 mg/mL at 25° C).
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