Patulin, a mycotoxin, has been reported to contain antibiotic characteristics. This compound displays the ability to specifically inhibit Na+-K+ ATPase. In murine studies, Patulin was found to inhibit protein prenylation in cells. Mechanistic studies suggest that Patulin reduces incorporation of mevalonate into proteins and prevents protein transferase action, which is required for protein prenylation. Additional experiments show that this mycotoxin also inhibits cell-free microtubule polymerization by covalently reacting with thiol groups of microtubule proteins.
1. Riley, R.T., et al. 1990. Toxicol. Appl. Pharmacol. 102: 128-141. PMID: 2153317 2. Miura, S., et al. 1993. FEBS Lett. 318: 88-90. PMID: 8436232 3. Pfeiffer, E., et al. 1998. Carcinogenesis. 19: 1313-1318. PMID: 9683194
Hepatitis C virus NS3 protease/helicase: IC50 = 3800 nM (Hepatitis C virus)
pKa: 11.69 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
UN 3462, Class 6.1, Packing group II
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Thank you to answer my question but I mean SDS of the monoclonal Antibody Patulin from rabbit?Thanks
Asked by: Al Rubaye
Thank you for your question. We do not offer an antibody against Patulin. Please contact our European Technical Service team, we would be happy to discuss this further with you. You can reach us by phone at Toll Free: +49 6221 4503 0, by email at: firstname.lastname@example.org or by live chat directly on our website, www.scbt.com
Answered by: Tech Service
Date published: 2017-11-28
Hello, my question is how can I get the Safety Data Sheet (SDS) for antibody putulin?Thanks
Asked by: Al Rubaye
Thanks you very much for your inquiry. Unfortunately, we don't offer any antibody against that protein. If you have any further question, please do not hesitate to contact us via email: email@example.com
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn
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