Papuamine A pentacyclic alkaloid and antifungal agent

Papuamine (CAS 112455-84-2)

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Synonym: (-)-Papuamine
Application: A pentacyclic alkaloid and antifungal agent
CAS Number: 112455-84-2
Molecular Weight: 368.6
Molecular Formula: C25H40N2
* Refer to Certificate of Analysis for lot specific data (including water content).
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Papuamine is a pentacyclic alkaloid with antifungal and antimycobacterial activity. The compound has a C2-symmetric structure and was originally isolated from marine sponges of the genus Haliclona. Papuamine has been shown to inhibit the growth of the dermatophyte Trichophyton mentagrophytes, and can be screened with the use of Mycobacterium marinum.


References

1. Barrett, A.G., et al. 1996. J. Org. Chem. 61: 685-699. PMID: 11666992
2. McDermott, T.S., et al. 1996. J. Org. Chem. 61: 700-709. PMID: 11666993
3. Barker, L.P., et al. 2007. Planta Med. 73: 559-563. PMID: 17534789

Appearance :
Amorphous
Physical State :
Solid
Derived From :
Haliclona sp.
Solubility :
Soluble in DMSO, methanol or 100% ethanol; poorly soluble in water.
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Transport :
Regional sales restrictions may apply.
PubChem CID :
10248478
SMILES :
C1C[C@@H]2[C@H]([C@H]\\3[C@@H](C2)NCCCN[C@H]4[C@H]([C@H]5[C@H](C4)CCCC5)/C=C/C=C3)CC1

Download SDS (MSDS)

Certificate of Analysis

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