PACAP(6-38), human, ovine, rat A hypothalamic peptide that affects anterior pituitary cell function

PACAP(6-38), human, ovine, rat (CAS 137061-48-4)

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Synonym: Pituitary adenylate cyclase-activating peptide
Application: A hypothalamic peptide that affects anterior pituitary cell function
CAS Number: 137061-48-4
Molecular Weight: 4024.8
Molecular Formula: C182H300N56O45S
* Refer to Certificate of Analysis for lot specific data (including water content).
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PACAP(6-38) is a hypothalamic peptide that affects anterior pituitary cell function. It also plays a key role in the embryogenesis of brain, protection of brain nerve cells from ischemia-induced death, injuring and apoptosis.


References

Chepurnov SA, Chepurnova NE, Ponomarenko AA et al. Usp Fiziol Nauk. 30:3-20 (1999). Arbogast LA, Voogt JL. Brain Res. 655:17-24 (1994).

Physical State :
Solid
Sequence :
Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-Gly-Lys-Arg-Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys-NH2
Storage :
Store at 4° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
24868185
SMILES :
C[C@H]([C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC3=CC=C(C=C3)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC4=CC=C(C=C4)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)N)NC(=O)[C@H](CC5=CC=CC=C5)N)O

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