Oxytetracycline is an anti-inflammatory, antibiotic, and anti-proliferative agent shown to inhibit mitochondrial protein synthesis. Mechanistic studies show that this compound reduces cytochrome c activity which eventually causes cell growth arrest. Additionally, Oxytetracycline has demonstrated the ability to reduce murine bronchial inflammation. The anti-inflammatory characteristics of this agent are due to its ability to cause a decrease in IL-4, IL-5, IL-13, immune cells, and the ovalbumin-specific IgE. Data suggests that Oxytetracycline is also an inhibitor of NF-κB activation via phosphorylation and degradation of IκB-α.
1. van den Bogert, C., et al. 1981. Cancer Res. 41: 1943-1947. PMID: 7214362 2. van den Bogert, C., et al. 1983. Cancer Res. 43: 2247-2251. PMID: 6831447 3. Ci, X., et al. 2010. J. Clin. Immunol. [Epub ahead of print]. PMID: 21136283
Soluble in DMSO (92 mg/ml at 25° C), water (<1 mg/ml at 25° C), and ethanol (10 mg/ml at 25° C).
Store at room temperature
~727.8° C at 760 mmHg (Predicted)
~1.7 g/cm3 (Predicted)
n20D 1.76 (Predicted)
α20/D -196.6° in 0.1 N HCl; α20/D -2.1° in 0.1 N NaOH; α25/D +26.5° in methanol
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Adobe Acrobat Reader is required to reliably view, print and comment on PDF documents
bvseo_sdk, java_sdk, bvseo-3.2.0
CLOUD, getContent, 115ms
bvseo-msg: The resource to the URL or file is currently unavailable.;
Rated 5 out of
SeoSeo, HB. et al. (PubMed 26334055) presented a a novel reflectance-based colorimetric aptasensor using gold nanoparticles for the detection of Oxytetracycline for the first time. They were able to detect Oxytetracycline at concentrations as low as 1nM in both buffer solution and tap water. -SCBT Publication Review
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn
Create a new account
Email address already exists, please enter a new valid email address.
USE YOUR SOCIAL NETWORK
Create an account quickly and easily with your preferred social network account. You won't have to remember an extra name and password.
Creating an account with us makes your shopping experience much easier and faster. You can save favorites, save cart, check order status and speed through checkout with saved addresses, payment methods and more.