Osmium tetroxide Osmium tetroxide is widely used to oxidise alkenes to the vicinal diols, adding two hydroxyl groups at the same side (syn addition).

Osmium tetroxide  (CAS 20816-12-0)

Osmium tetroxide is rated 5.0 out of 5 by 1.
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| See 3 Citations
Synonym: Osmium(VIII)-oxide
Application: A hydroxyl-donating compound for chemical synthesis
CAS Number: 20816-12-0
Purity: ≥98%
Molecular Weight: 254.23
Molecular Formula: OsO4
* Refer to Certificate of Analysis for lot specific data (including water content).
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Ordering Information

PRODUCT NAME CATALOG # UNIT PRICE QTY FAVORITES
Osmium tetroxide sc-206008 250 mg $72.00
Osmium tetroxide sc-206008A 1 g $217.00

Osmium tetroxide is widely used to oxidise alkenes to the vicinal diols, adding two hydroxyl groups at the same side (syn addition). It is also used in catalytic amounts in the Sharpless oxyamination to give vicinal amino-alcohols. Osmium tetroxide is also a widely used staining agent used in transmission electron microscopy (TEM) to provide contrast to the image.

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in water (72 mg/ml), alcohol, ether, and chloroform (3750 mg/ml).
Storage :
Store at room temperature
Melting Point :
39.5-41° C (lit.)
Boiling Point :
130° C (lit.)
Density :
4.9 g/cm3
Refractive Index :
n20D 1.33
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
1
RTECS :
RN1140000
Transport :
UN 2471, Class 6.1, Packing group I
PubChem CID :
30318
Merck Index :
14: 6893
MDL Number :
MFCD00011150
EC Number :
244-058-7
SMILES :
O=[Os](=O)(=O)=O

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Osmium tetroxide Product Citations

See how others have used Osmium tetroxide. Click on the entry to view the PubMed entry .

Citations 1 to 3 of 3 total

PMID: # 23169061
Pellegrini, C. et al. 2013. Melanocytes--a novel tool to study mitochondrial dysfunction in Duchenne muscular dystrophy. J. Cell. Physiol.. 228: 1323-1331.

PMID: # 22711985
Blättler, SM. et al. 2012. Defective mitochondrial morphology and bioenergetic function in mice lacking the transcription factor Yin Yang 1 in skeletal muscle. Mol. Cell. Biol.. 32: 3333-3346.

PMID: # 22200571
Sekimoto, J. et al. 2012. Dissociation of the insulin receptor from caveolae during TNFα-induced insulin resistance and its recovery by D-PDMP. FEBS Lett.. 586: 191-195.

Citations 1 to 3 of 3 total
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Rated 5 out of 5 by from Various publications cite the use the Osmium Various publications cite the use the Osmium tetroxide stain to oxidize alkenes to vicinal diols and also as a common contrast agent in transmission electron microscopy. -SCBT Publication Review
Date published: 2015-02-07
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