Nocardamine A cyclic siderophore

Nocardamine  (CAS 26605-16-3)

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Synonym: deferrioxamine E
Application: A cyclic siderophore
CAS Number: 26605-16-3
Purity: ≥98%
Molecular Weight: 600.70
Molecular Formula: C27H48N6O9
* Refer to Certificate of Analysis for lot specific data (including water content).
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Nocardamine is a cyclic siderophore. Stimulates secondary metabolite formation and morphological differentiation in various actinomycete strains. Also induces morphological changes in insect cells.


References

The description and antibiotic production of Streptomyces hygroscopicus var. Geldanus.: C. BeBoer & A. Dietz; J. Antibiot. 29, 1182 (1976) Desferrioxamine E produced by Streptomyces griseus stimulates growth and development of Streptomyces tanashiensis.: K. Yamanaka, et al.; Microbiology 151, 2899 (2005) Siderophore production by Pseudomonas stutzeri under aerobic and anaerobic conditions.: S.A. Essén, et al. ; Appl. Environ. Microbiol. 73, 5857 (2007)

Physical State :
Solid
Derived From :
Streptomyces sp. K04-0144.
Solubility :
Soluble in water, DMSO, and hot methanol. Insoluble in chloroform, ethyl acetate, and hexane.
Storage :
Store at -20° C
Density :
1.16 g/cm3
Refractive Index :
n20D 1.50
IC50 :
Exodeoxyribonuclease V gamma chain: IC50 = >118.6 µM (Escherichia coli ); Staphylococcus aureus sortase B: EC5050 = >200 ug.mL-1; Exodeoxyribonuclease V alpha chain: IC50 = >118.6 µM (Escherichia coli); Exodeoxyribonuclease V beta chain: IC50 = >118.6 µM (Escherichia coli)
pK Values :
pKa: 8.64 (Predicted), pKb: 0.14 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
161532
MDL Number :
MFCD08457937
Beilstein Registry :
381704
SMILES :
C1CCNC(=O)CCC(=O)N(CCCCCNC(=O)CCC(=O)N(CCCCCNC(=O)CCC(=O)N(CC1)O)O)O

Download SDS (MSDS)

Certificate of Analysis

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