Nisin from Lactococcus lactis An antibiotic with bactericidal action

Nisin from Lactococcus lactis (CAS 1414-45-5)

Nisin from iLactococcus lactis/i | CAS 1414-45-5 is rated 5.0 out of 5 by 1.
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Application: An antibiotic with bactericidal action
CAS Number: 1414-45-5
Molecular Weight: 3354.07
Molecular Formula: C143H230N42O37S7
* Refer to Certificate of Analysis for lot specific data (including water content).
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Antibiotic with bactericidal action. Binds to the lipid A portion of bacterial lipopolysaccharides. Induces pore formation in the membranes of cortex cells from excised sorghum roots. Mode of Action: Binds to and interferes with the permeability of the cytoplasmic membrane. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria (requires chelator such as EDTA).


References

Cornu, J. Ann. Microbiol. 131B, 121, (1980) Storm, D.R., et al. Annu. Rev. Biochem. 46, 723, (1977) Morrison, D.C. and Jacobs, D.M. Immunochemistry 13, 813, (1976) Lerner, H.R., et al. Physiol. Plant. 57, 90, (1983)

Formulation :
2.5% (balance sodium chloride and denatured milk solids)
Appearance :
Powder
Physical State :
Solid
Storage :
Store at 4° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
16133879
MDL Number :
MFCD00131724
SMILES :
CCC(C)C1C(=O)NC(=C)C(=O)NC(C(=O)NC(CSCC(C(=O)N1)NC(=O)/C(=C/C)/NC(=O)C(C(C)CC)N)C(=O)NC2C(SCC(NC(=O)CNC(=O)C3CCCN3C2=O)C(=O)NC(CCCCN)C(=O)NC4C(SCC(NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)CNC4=O)C)CC(C)C)CCSC)C(=O)NC(CC(=O)N)C(=O)NC(CCSC)C(=O)NC(CCCCN)C(=O)NC5C(SCC6C(=O)NC(C(=O)NC(CSC(C(C(=O)N6)NC(=O)C(NC5=O)C)C)C(=O)NC(CO)C(=O)NC(C(C)CC)C(=O)NC(CC7=CN=CN7)C(=O)NC(C(C)C)C(=O)NC(=C)C(=O)NC(CCCCN)C(=O)O)CC8=CN=CN8)C)C)C)CC(C)C

Download SDS (MSDS)

Certificate of Analysis

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Hallo, What purity of nisin?

Asked by: Gintes
Thank you for your question. Each lot of this chemical comes with a lot-specific Certificate Of Analysis which typically describes the percent purity as well as the method used to determine the purity. You may request a lot-specific Certificate Of Analysis on our website. Alternatively, please contact our Technical Service Department to inquire about the purity of our most recent lot. Please call our European Support office toll-free at 00800 4573 8000, email europe@scbt.com, or contact us by live chat.
Answered by: Technical Support
Date published: 2016-10-20
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Rated 5 out of 5 by from Joo Joo, NE. et al. (PubMed 23342279) reported that Nisin, an apoptogenic bacteriocin and food preservative, attenuates HNSCC tumorigenesis via CHAC1 in HNSCC cells. -SCBT Publication Review
Date published: 2015-04-03
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